Open Biosystems offers a complete platform for antibody-based biomarker development utilizing cutting-edge
antigen design and antibody screening tools. Take advantage of Open’s
peptide synthesis,
protein expression,
polyclonal and or
monoclonal antibody development and antibody production services to generate robust reagents that are designed to perform in your specific
assay application. See what a difference an integrated platform can make in your research and pre-clinical applications.
Antibody Biomarker Development
- Comprehensive antigen design with Antigen Profiler
- Peptide synthesis or protein expression
- Targeted Antigen Display (conjugation and antigen manipulation)
- Polyclonal and/or monoclonal development
- Antibody production and purification
Open Bio has the largest
cDNA clone collection in the world from which we can take clones and subclone into suitable expression vectors for bacterial or mammalian
protein expression. Antibodies generated can be screened and optimized for quantitative ELISA, IHC, or multiplex formats such as MSD, Luminex, and Singulex platforms.
Antibody Matched Pair Development
Antibodies suitable for capture and detection generated from any of our Biomarker Development Options can be developed for specific assay formats including traditional ELISA, MSD, and Luminex platforms.
- Capture antibody optimization through IP screening
- Capture antibody optimization through secondary capture immobilization
- Antibody-bead bound screening
- Distinct antibody site recognition through direct labeling and inhibition screening
- Heterogeneous or homogenous species formats
- Polyclonal-polyclonal, monoclonal-polyclonal, or monoclonal-monoclonal formats
- Competitive or sandwich ELISA format and standard development
All projects and options are done with milestone pricing to defer costs. For more information on any of our comprehensive biomarker development options or other antibody services, email a project manager at
abs@openbiosystems.com or call us toll-free.
