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LentiORF (HA/Myc) Druggable Set   call call
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Druggable LentiORFs
an efficient path to drug target identification
Druggable genes (as defined by Hopkins and Groom1) encode proteins with domains that are known active sites for the binding of endogenous small molecules and have been found experimentally to bind drug-like (orally bioavailable) organic compounds.

Human LentiORF Druggable Sets each include more than 800 ORFs derived from genes that contain one or more druggable InterPro protein domains.1,2 Screening  with this subset of the ORFeome to determine which ORFs are also disease related is an efficient path to drug target identification.

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Clone Collections:
Orders of 50 clones or greater and stock plates will be provided in 96-well microtiter plates. These will ship on dry-ice via overnight delivery and should be stored at –80°C immediately upon receipt. Please contact our customer service department for a quote and estimated shipping time on bulk orders.



References:
1Hopkins AL, Groom CR (2002). The druggable genome. Nature Reviews Drug Discovery 1, 727-730

2Orth AP at al (2004). The promise of genomics to identify novel therapeutic targets. Expert Opin. Ther. Targets8, 587-596


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