The Cancer Chromosome Aberration Project (CCAP), a joint initiative supported by the NCI and NCBI, aims to develop tools that assist in the analysis of chromosomal aberrations associated with malignant transformation. To meet this objective, CCAP generated a set of cytogenetically FISH-mapped BAC clones at a resolution of 1-2MB across the human genome. The BACs have been physically mapped to the genome using sequence tag sites (STS) and ordered using genetic linkage and/or radiation hybrid mapping data. Additionally, these clones are FISH mapped onto pro-metaphase spreads to allow high resolution placement, uniform coverage of the chromosomes, and their precise positioning relative to one another. This resource is the first collection to effectively integrate the cytogenetic and sequence maps of the human genome, thus facilitating the transition to molecular cytogenetics¹ .

The CCAP FISH-mapped BACs are linked to databases containing clinical data and histopathologic information. Additionally, links are provided to databases containing associated genomic and genetic data such as end sequence or gene information. Thus once a region or BAC clone of interest is identified you can quickly and easily correlate your data with that of others.

To find a BAC clone covering a particular region: