Human pSM2 shRNAmir gene familiy and pathway sets provide the advantages of shRNAmir design combined with the convenience of Gene Ontology (GO) annotated collections targeting all genes in a particular gene family or biological pathway. The arrayed sets contain shRNAmir from the human pSM2 lentiviral shRNAmir library that target all genes falling under specific GO terms. These collections will greatly simplify pathway analysis, target identification and validation.Available human pSM2 retroviral shRNAmir libraries include:| Angiogenesis | 109
| 352
|
| Apoptosis | 767
| 2397
|
| Cell Cycle | 790
| 2191
|
| GPCRs | 655
| 1867
|
Kinases
| 782
| 2503
|
Phosphatases
| 156
| 548
|
Transcription Factors
| 840
| 2672
|
Ubiquitins
| 148
| 605
|
Ubiquitin-Ligases
| 350
| 1558
|
GO annotations are applied to genes by curators within the Gene Ontology Consortium and do not originate from Open Biosystems. Consult the Gene Ontology website for details. Click here for more information about the pSM2 shRNA library.
The shRNAmir rearrays of gene families are provided in 96-well microtiter plates containing frozen stock cultures of E. coli (DH10bpir116) in LBR broth with 8% glycerol and chloramphenicol (50ug/ml). Open Biosystems checks all cultures for growth prior to shipment. Store at -80ºC.