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Product Licenses

Limited Use License #2007A
Tetracycline Inducible Systems

Use of the Tetracycline controllable expression systems (the "Tet Technology") is covered by a series of patents including U.S. patents # 5,464,758 and #5,814,618, which are proprietary to TET Systems Holding GmbH & Co. KG. Academic research institutions are granted an automatic license with the purchase of this product to use the Tet Technology only for internal, academic research purposes, which license specifically excludes the right to sell, or otherwise transfer, the Tet Technology or its component parts to third parties. Notwithstanding the above, academic and not-for profit research institutions who’s research using the Tet Technology is sponsored by for profit organizations, which shall receive ownership to all data and results stemming from the sponsored research, shall need a commercial license agreement from IP Merchandisers in order to use the Tet Technology. In accepting this license, all users acknowledge that the Tet Technology is experimental in nature. TET Systems Holding GmbH & Co. KG makes no warranties, express or implied or of any kind, and hereby disclaims any warranties, representations, or guarantees of any kind as to the Tet Technology, patents, or products. All others are invited to request a license from TET Systems Holding GmbH & Co. KG prior to purchasing these reagents or using them for any purpose. Open Biosystems is required by its licensing agreement to submit a report of all purchasers of the Tet-controllable expression system to IP Merchandisers, Inc.

For license information, please contact:

Hans Peter Kneubuehl
TET Systems Holding GmbH & Co. KG
Im Neuenheimer Feld 582
69120 Heidelberg, Germany
Tel +49 6221 588 04 00
Fax +49 6221 588 04 04

email: kneubuehl@tet-systems.com

or use our electronic licensing request form via http://www.tetsystems.com/main_inquiry.htm


Limited Use License #2007B
miRNA Adapted shRNA Clones

Portions of this product are covered by several patent applications owned by Duke University (DUKE). The purchase of this product conveys to the buyer the limited, non-exclusive, non-transferable right (without the right to resell, repackage, or further sublicense) under these patent rights to perform the miRNA methods using the shRNAmir-inducing vectors claimed in those patent applications for research purposes solely in conjunction with this product. No other license is granted to the buyer whether expressly, by implication, by estoppel or otherwise. In particular, the purchase of this product does not include nor carry any right or license to use, develop, or otherwise exploit this product commercially, and no rights are conveyed to the buyer to use the product or components of the product for any other purposes, including without limitation, provision of services to a third party, generation of commercial databases, or clinical diagnostics or therapeutics.

This product is sold pursuant to a license from DUKE, and DUKE reserves all other rights under these patent rights. For information on purchasing a license to the patent rights for uses other than in conjunction with this product or to use this product for purposes other than research, please contact the Duke Office of Technology Transfer at, 919-684-3131.


Limited Use License #2007C
Evrogen Fluorescent Proteins

This product contains a proprietary nucleic acid(s) coding for a proprietary fluorescent protein(s) being, including its derivatives or modifications, the subject of pending U.S. and foreign patent applications and/or patents owned by Evrogen JSC (hereinafter “Evrogen Fluorescent Proteins”).
The purchase of this product conveys to the buyer the non-transferable right to use Evrogen Fluorescent Proteins for (i) not-for-profit internal Research conducted by the buyer (whether the buyer is an academic or for-profit entity), where “Research” means non-commercial uses or activities which (or the results of which) do not generate revenue, and (ii) evaluation of Evrogen Fluorescent Proteins for the purpose of testing its appropriateness for development of a therapeutic, clinical diagnostic, vaccine or prophylactic product, provided that Evrogen Fluorescent Proteins are not used in the development or manufacture of such product.
Offer of Evrogen Fluorescent Proteins for resale; distribution, transfer, or otherwise providing access to Evrogen Fluorescent Proteins to any third party for any purpose, or any use of Evrogen Fluorescent Proteins other than for Research is strictly prohibited.
The buyer cannot sell or otherwise transfer materials made by the employment of Evrogen Fluorescent Proteins to a third party or otherwise use Evrogen Fluorescent Proteins for Commercial Purposes. The buyer may transfer information made through the use of this product solely for research and not for Commercial Purposes. Commercial Purposes means any activity by a party for consideration and may include, but is not limited to: (1) use of Evrogen Fluorescent Proteins in manufacturing; (2) use of Evrogen Fluorescent Proteins to provide a service, information, or data; (3) use of Evrogen Fluorescent Proteins for therapeutic, diagnostic or prophylactic purposes.
The purchase of this product does not convey a license under any method claims in the foregoing patents or patent applications.

For information on the foregoing patents or patent applications or on purchasing a license to use Evrogen Fluorescent Proteins for purposes other than those permitted above, contact Licensing Department,

Evrogen JSC,
Miklukho-Maklaya street 16/10,
Moscow, 117997, Russian Federation.

email: license@evrogen.com.


Limited Use License #2006A
Trans-Lentiviral Packaging Systems

Portions of this product are covered by several patent applications owned by, or licensed to, Tranzyme, Inc. The purchase of this product conveys to the buyer the limited, non-exclusive, non-transferable right (without the right to resell, repackage, or further sublicense) under these patent rights to perform the viral infection methods using the lentiviral vectors claimed in those patent applications for research purposes solely in conjunction with this product. No other license is granted to the buyer whether expressly, by implication, by estoppel or otherwise. In particular, the purchase of this product does not include nor carry any right or license to use, develop, or otherwise exploit this product commercially, and no rights are conveyed to the buyer to use the product or components of the product for any other purposes, including without limitation, provision of services to a third party, generation of commercial databases, or clinical diagnostics or therapeutics.

This product is sold pursuant to a license from Tranzyme, Inc., and Tranzyme, Inc. reserves all other rights under these patent rights. For information on purchasing a license to the patent rights for uses other than in conjunction with this product or to use this product for purposes other than research, please contact the licensing officer at 256-319-1462.


Limited Use License #2005A
shRNA Clones

Permitted Use. Portions of this product are covered by published patent applications (the "shRNA IP Rights") owned by Cold Spring Harbor Laboratory, referred to herein as “CSHL.” This product, and/or any components or derivatives of this product, and/or any materials made using this product or its components, are referred to herein as the “Product.” Subject to the terms of this Limited Use Agreement, sale of the Product by Open Biosystems (“OBS”) conveys the limited, nonexclusive, nontransferable right to any company or other entity that orders, pays for and takes delivery of the Product (the “Customer”) from OBS to use the Product solely for its internal research and only at such Customer’s facility where the Product is delivered by OBS.

Restrictions. Customer obtains no right to transfer, assign, or sublicense its use rights, or to transfer, resell, package, or otherwise distribute the Product, or to use the Product for the benefit of any third party or for any commercial purpose. The Product or components of the Product may not be used in vitro or in vivo for any diagnostic, preventative, therapeutic or vaccine application, or in the manufacture or testing of a product therefor, or used (directly or indirectly) in humans for any purpose.

Compliance. Customer may only use the Product in compliance with applicable local, state and federal laws, regulations and rules, including without limitation (for uses in the United States) EPA, FDA, USDA and NIH guidelines. Customer may not (directly or indirectly) use the Product, or allow the transfer, transmission, export or re-export of all or any part of the Product, in violation of any export control law or regulation of the United States or any other relevant jurisdiction.

Other Uses. Except for the permitted use expressly specified above and subject to the restrictions set forth above, no other use is permitted. CSHL shall retain all right, title and interest in and to the shRNA IP Rights. Nothing herein confers to Customer (by implication, estoppel or otherwise) any right or license under any patent of CSHL, including, for avoidance of doubt, under any patent that may issue from or relate to the shRNA IP Rights. For information on obtaining an agreement to use this Product for purposes other than those expressly permitted by this Limited Use Agreement, or to practice under CSHL patent rights, please contact the CSHL Office of Technology Transfer at (516) 367-8301.

Termination of Rights. Upon issuance of any patent covering any portion of the Product, any and all rights conveyed to any Customer (other than a research or educational institution that is a tax-exempt organization under section 501(c)(3) of the U.S. IRS code) under this Limited Use Agreement shall terminate and such Customer shall need a license from CSHL to continue to use any Product that was previously purchased, or to purchase from OBS or any other vendor or use any product claimed by such issued patent. At such time, such Customer may contact the CSHL Office of Technology Transfer at (516) 367-8301 and seek a license to use this Product under CSHL’s patent rights.

YOUR USE OF THIS PRODUCT CONSTITUTES ACCEPTANCE OF THE TERMS OF THIS LIMITED USE AGREEMENT. If you are not willing to accept the limitations of this agreement, OBS is willing to accept return of the Product for a full refund.


Limited Use License #2004A
Incyte cDNA Clones

This limited license permits the person or legal entity to which this product has been provided to use the product and the data generated by the use of this product, only for its internal research purposes. In addition, Buyer acknowledges and agrees that it is not licensed to (a) provide commercial data or databases to or on behalf of any third party that relate to the use of the product; or (b) use the product or data therefrom in a clinical diagnostic setting where data resulting from the testing of an individual’s sample is given to such individual or their physician or caregiver. Licensor and its licensors expressly disclaim any warranties of non-infringement. Neither Licensor or its licensors grants any other licenses, express or implied to permit the manufacture, use, sale or importation of this product.

Questions regarding this Limited Label License can be addressed to licensing@openbiosystems.com


Limited Use License #2004A
Exelixis cDNA Clones

This limited license permits the person or legal entity to which this product has been provided to use the product only for its internal research purposes. In addition, Buyer acknowledges and agrees that it is not licensed to use the product in a clinical diagnostic setting where data resulting from the testing of an individual’s sample is given to such individual or their physician or caregiver. Licensor and its licensors expressly disclaim any warranties of non-infringement. Neither Licensor or its licensors grants any other licenses, express or implied to permit the manufacture, use, sale or importation of this product.
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