Open Biosystems’ Open Access™ RNAi Program Provides Peter MacCullum Cancer Centre with shRNAmir Technology

Expanding Program Brings Latest RNAi Tools to Leading Cancer Centers Worldwide

HUNTSVILLE, Ala.—June 6, 2006—Open Biosystems, Inc., focused on the commercialization of leading-edge life science research tools for drug discovery, today announced that the Peter MacCullum Cancer Centre, the only hospital in Australia dedicated to cancer research, treatment and care, has joined its Open Access RNAi Program. Through this program, the Peter MacCullum Cancer Centre has purchased Open Biosystems’ whole genome human lentiviral shRNAmir library.

By participating in the Open Access RNAi program, the hospital’s community of 265 researchers is provided with the most advanced RNAi technology targeting the entire human genome with multiple constructs per gene. With this unique technology access model, program participants receive continual updates and upgrades as extensions of the libraries are released. The Open Access RNAi Program also provides off-site backups and a partner specific technical support team.  This leading-edge whole-genome resource enables all Peter MacCullum Cancer Centre investigators to target any gene in the human genome with improved knockdown efficiency and effectiveness.

“Our research division is one of the world’s largest groups dedicated solely to cancer research, and we deeply value collaborative integration with local, national and international institutions,” said Ricky Johnstone, principal investigator at the Peter MacCullum Cancer Centre. “Open Biosystems supports our mission to develop the very best cancer treatment by granting us the most advanced shRNA technology at a fraction of the cost compared to the purchase of libraries as individuals. The libraries allow us to conduct RNAi-based studies to develop new technologies that will result in significant breakthroughs in biomedical research.”
 

“World-renowned research organizations continue to experience and appreciate the value of shRNAmir technology through the Open Access Program, with participation in the program expanding throughout the globe,” said Troy Moore, chief technical officer and co-founder of Open Biosystems. “The Peter MacCullum Cancer Centre exemplifies the benefits that a whole genome RNAi resource provides to advancing scientific research and underscores our commitment to furthering all aspects of cancer research.”

About RNAi
RNAi is a mechanism cells use to naturally regulate gene expression. It is being increasingly harnessed as a tool to identify and understand genes that function in the disease process, especially in cancer research. Open Biosystems is the leading provider of mammalian RNAi resources and its RNAi portfolio includes leading-edge technology incorporating advances in shRNA design and captured in whole genome microRNA-adapted shRNA (shRNAmir) libraries. Open Biosystems' shRNAmir libraries are proven to provide greater gene knockdown and fewer off-target effects than other RNAi systems.
Additional information about Open Biosystems’ Open Access RNAi Program can be found online at www.openbiosystems.com/OpenAccessRNAi.

About Open Biosystems
Open Biosystems, Inc. develops, manufactures and markets genomic research tools to scientists and researchers in corporate, academic and government laboratories. These research tools provide investigators with standardized high-quality genes, RNAi and antibodies for interrogating gene function in relation to oncology, neuroscience and metabolic disorders. Founded in 2001, Open Biosystems is headquartered in Huntsville, Alabama. For more information and details for ordering, please visit www.openbiosystems.com.

Contacts:

Laura Huckabee-Jennings
256.325.7212
Open Biosystems
Laura.Huckabee-Jennings@openbiosystems.com

Lauren Arnold or Stacey Holifield
781.684.0770
Schwartz Communications
openbiosystems@schwartz-pr.com

© 2005-2007 Open Biosystems All Rights Reserved