Peptide and Protein Antigen Design with Antigen ProfilerTM Open Biosystems has designed a set of powerful algorithms that enables researchers to have protein sequences analyzed to select the best peptides for antibody production. Antigen Profiler is the the complete peptide antigen design tool.
- Examine comparative antigenicity based upon actual in vivo titer data from over 13,000 peptide antibodies
- Incorporate important structural motifs that are proven sites for producing high binding antibodies
- Built-in peptide tutorial for synthesis and solubility
- Specificity determination through curated BLAST analysis
Advanced Protein Analysis
Antigen ProfilerTM compiles bioinformatic data based on epitope mapping, secondary structural analysis and comparative antigenicity to design antibodies with greater collective utility across assay formats. Sophisticated computational algorithms identify active sites, signal peptides, splice variants and over a dozen additional features including:
Our internal analysis program searches and accesses your sequence to identify the best candidate peptides that optimize synthesis success, solubility and antigenicity. Each peptide is compared with our curated BLAST databases of over two dozen species to limit cross-reactivity while improving overall antibody specificity. When you have peptides designed with Antigen Profiler you are in control: Target post-translational modifications
Avoid epitopes unavailable due to structural constraints
Specify desirable cross-reactivity
Eliminate re-synthesis times with built-in peptide tutorial for synthesis and solubility
Choose the best antigen conjugation and presentation options for your desired assay(s)
Customer Report
With each custom antibody project, you receive a complete protein analysis and peptide design report. Antigen ProfilerTM graphically displays protein characteristics and automated interactive BLAST data. Output report includes:
In addition to our Antigen Profiler, dedicated project managers with experience in making over 16,000 polyclonal antibodies and 500 monoclonal antibodies work with you from the beginning to the end of your project and ensure the highest level of sevice. Using powerful selective criteria, they help you design antigens that mimic the presentation of epitopes in native proteins and produce antibodies to meet your exacting criteria.
For additional information on our antibody services or to request a quote and Antigen Profile, please visit the following links:
Frequently Asked Questions
Antibody Uses and Applications
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Antibody References
