Carrier Protiens Researchers may select from the following list of common carrier proteins or submit to have another protein used.
- KLH: keyhole lympet hemocyanin
- BSA: bovine serum albumin
- OVA: ovalbumin
- THY: thyroglobulin
Open Biosystems does not recommend amidation or acetylation of terminal residues unless the peptide is being used for kinematic studies or a previous method is being imitated. The chemistries used solely or in combination to present optimal, assay specific epitopes for Targeted Antigen Display are as follows:
Gluteraldehyde: Links peptides to KLH through the n-terminus of the peptide with minor side chain reactions.
Carbodiimide (EDC): Attaches peptides through the c-terminus to KLH. Internal linkage to side chain carboxylic acids is controlled through time and linker concentration.
Maleimide: This chemistry is used when peptide sequences contain cysteines. An alternative linker used instead of the traditional MBS form that is smaller. This minimizes the number of antibodies produced to the linker.
PNPI: Used to link through hydroxyl groups when certain conditions are met.
Dityrosine: Tyrosines can be used to cross-link peptides to form cyclic structures or conjugate one peptide to another species of antigen. Oxidative conditions are used to drive this highly specific, covalent bond.
For more information on our polyclonal animal services, please visit Custom Polyclonal Antibodies.
Frequently Asked Questions
Antibody Uses and Applications
Why Order from Open Biosystems?
Antibody References
